Extended Data Fig. 7: TI-derived MBCs are not GCBC-derived. | Nature Immunology

Extended Data Fig. 7: TI-derived MBCs are not GCBC-derived.

From: Memory B cell subsets have divergent developmental origins that are coupled to distinct imprinted epigenetic states

Extended Data Fig. 7

a, Number of total MBCs at Day 5 (left) and Day 28 (right) between NP-CGG + PBS control (day 5; n = 4, day 28, n = 6) and NP-CGG + GK1.5 + FGK (day 5; n = 6, day 28, n = 5) treated mice. b, Representative flow plots of NIP+ MBCs from BALBc transfer system under indicated immunizations at week 4. c, Number of MBC subsets per spleen for each indicated immunization. d, Representative flow plots of NIP+ MBCs from BALB/c transfer system under indicated immunizations at week 4, showing gating to determine GC-derived MBCs. e, left: percent of; right: number of; total MBCs displaying a GC-derived phenotype in the 4 different immunizations. For b-e, n = 3, except NP-CGG + FGK + GK1.5, where n = 4. Bars display mean ± s.d. P-values were calculated using two-tailed Welch’s t-test (*P < = 0.05). Actual p-values are listed in source data.

Source data

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