Extended Data Fig. 1: Distinct transcriptomic and epigenetic profiles of FO NBCs and MBC subsets. | Nature Immunology

Extended Data Fig. 1: Distinct transcriptomic and epigenetic profiles of FO NBCs and MBC subsets.

From: Memory B cell subsets have divergent developmental origins that are coupled to distinct imprinted epigenetic states

Extended Data Fig. 1

a, PCA plot of genes with expression of >= 0 log2 normalized reads in at least one cell type (n=3 per cell type). b, PCA plot of OCRs with accessibility of >= 1 log2 normalized reads in at least one cell type (n=2 per cell type). c,d, Boxplots showing relative PageRank score for TFs with higher (c) or lower (d) scores in all MBC subsets compared to FO naïve. Boxplots display median values and lower and upper quartiles, the ranges display min and maximum values. n= 2 per cell type.

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