Extended Data Fig. 5: PG16-Db and 3BNC117-Db do not eliminate cells harboring defective proviruses ex vivo.
From: Bispecific antibodies promote natural killer cell-mediated elimination of HIV-1 reservoir cells
Frequencies of CD4+ T cells harboring a, 5′ deleted or b, 3′ deleted or hypermutated proviruses after treatment with PMA+I and co-culture with autologous NK cells in the presence of PG16-Db, 3BNC117-Db, or PG16-Db+3BNC117-Db. Data reported as defective HIV-1 copies per million viable CD4+ T cells (mean, SD) from eight replicates.
