Extended Data Fig. 8: Additional measures of H2-Db and 3BNC117-Db-mediated activity in hIL-15TgNSG mice.
From: Bispecific antibodies promote natural killer cell-mediated elimination of HIV-1 reservoir cells
Plasma viremia and peripheral blood NK cell activity in the hIL-15TgNSG mice prior to infection, at the time of ART initiation, and before and after H2-Db and 3BNC117-Db treatment. Data reported as HIV-1 RNA copies/mL plasma (top left), percentage of CD3-CD56+ lymphocytes (top right), percentage of HLA-DR+ NK cells (bottom left), and percentage of CD57+ NK cells (mean, SD). H2-Db (n = 9); 3BNC117-Db (n = 9). Significance determined by two-way ANOVA followed by Šídák’s test for multiple comparisons, *P < 0.05, **P < 0.01, ****P < 0.0001.
