Extended Data Fig. 5: Antibody-independent protection against heterologous SARS-CoV-2 infection conferred by prior mRNA vaccination.
(a–d) Frequency of CD8+ T cells (left) and CD4+ T cells (right) in the mediastinal lymph nodes (a, b) and spleens (c, d) of the indicated mice 4 days postinfection. Experimental setup is described in Fig. 5, and n of mice is indicated in Fig. 5a. Data are expressed as mean ± SEM. Data are representative of at least 2 independent experiments. *p value < 0.05, **p value < 0.01, ***p value < 0.001; Two-way ANOVA, Fisher’s LSD test (Each comparison stands alone) (a–d).
