Extended Data Fig. 6: Volcano plot of DEGs.
From: A method for predicting drugs that can boost the efficacy of immune checkpoint blockade
a-c, DEGs between response (R) and non-response (NR) samples of anti-PD-1 monotherapy (a), taltirelin monotherapy (b), and anti-PD-1 combined with taltirelin (c) groups in B16-F10 tumors on day 11 after treatment indicated in Extended Data Fig. 5a. Significantly (FDR < 0.05 and |log2FoldChange| > 1, P-values were calculated using a two-tailed Wald test, then FDR (BH) for correction of p-values. FDR values were used as criteria for significance filtering) activated and inhibited genes are highlighted in red and blue, respectively.
