Extended Data Fig. 4: IL-4/G-CSF polarized Ly6G+ BMN accumulate in the sciatic nerve at 4 hours, and the spinal cord at 24 hours, following SCI and i.n. BMN injection.

a, Representative section of a sciatic nerve harvested 4 hours after SCI injury and i.n. injection of IL-4/G-CSF polarized BMN that were derived from tdTomato-reporter mice. Donor BMN are identified as tdTomato⁺ (red) and Ly6G⁺ (white) (scale bar, 50 μm). b, Representative flow cytometric pseudocolored dot plot of mononuclear cells isolated from sciatic nerves 4 hours after SCI injury and i.n. injection of either IL-4/G-CSF polarized tdTomato⁺ BMN (left) or PBS (right), gating on CD11b⁺Ly6G⁺ cells. c, Representative flow cytometric pseudocolored dot plot of spinal cord mononuclear cells isolated 24 hours following SCI injury and i.n. injection of either IL-4/G-CSF polarized tdT⁺ BMN (left) or PBS (right), gating on CD11b⁺Ly6G⁺ cells. a-c, Data shown from one experiment, representative of two independent experiments.