Extended Data Fig. 1: Peripheral blood NK cell subsets and sorting strategy. | Nature Immunology

Extended Data Fig. 1: Peripheral blood NK cell subsets and sorting strategy.

From: Pan-cancer profiling of tumor-infiltrating natural killer cells through transcriptional reference mapping

Extended Data Fig. 1: Peripheral blood NK cell subsets and sorting strategy.

(a, b) AUCell scores of gene signatures for CD56bright and CD56dim NK regulones (a) and proteomes (b). (c, d) Sorting strategy for phenotypically defined functional PB-NK cell subsets sequenced in one donor with (c) and one without (d) an adaptive expansion. (e) Heatmap depicting similarity between our five annotated transcriptional NK cell subsets (y-axis) and the Meta-NK defined NK subsets (x-axis). The scale represent gene set activity calculated by AUCell (a-b, e).

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