Extended Data Fig. 7: Analysis of platelet-associated durability signature across vaccines and cell types. | Nature Immunology

Extended Data Fig. 7: Analysis of platelet-associated durability signature across vaccines and cell types.

From: System vaccinology analysis of predictors and mechanisms of antibody response durability to multiple vaccines in humans

Extended Data Fig. 7: Analysis of platelet-associated durability signature across vaccines and cell types.The alternative text for this image may have been generated using AI.

(a) Scatterplots of Day 7 vs Day 0 log2 fold changes (relative to last vaccination) of BTM M85 versus antibody residual in each vaccine dataset. Pearson correlation coefficient and p values are reported. (b) Heatmap of expression of platelet-associated BTMs across cell clusters in the CITE-seq data (Fig. 4). Colors represent row-wise z-scores of average expression of all genes in each module. (c) Scatterplots of Day 7 vs Day 0 log2 fold changes of platelet-expressed BTMs from PBMC (x-axis) and Paxgene (y-axis) samples in a cohort of healthy adults vaccinated with seasonal influenza vaccine. Pearson correlation coefficients and p values are reported.

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