Pulendran and colleagues define a molecular signature that can be used to predict the durability of antibody responses to vaccination and reveal important insights into the mechanisms by which vaccines induce durable immunity.
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References
Cortese, M. et al. Nat. Immunol. https://doi.org/10.1038/s41590-024-02036-z (2025).
Gaucher, D. et al. J. Exp. Med. 205, 3119–3131 (2008).
Querec, T. D. et al. Nat. Immunol. 10, 116–125 (2009).
Nakaya, H. I. et al. Immunity 43, 1186–1198 (2015).
Tsang, J. S. et al. Cell 157, 499–513 (2014).
Kotliarov, Y. et al. Nat. Med. 26, 618–629 (2020).
Kaczorowski, K. J. et al. Proc. Natl Acad. Sci. USA 114, e6097–e6106 (2017).
Brodin, P. et al. Cell 160, 37–47 (2015).
Davis, M. M. Immunity 29, 835–838 (2008).
Brodin, P., Duffy, D. & Quintana-Murci, L. Immunity 50, 1335–1336 (2019).
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P.B. is a cofounder of Cytodelics, an executive board member of Kancera and a scientific advisor for Pixelgen Technologies, Helaina, Scailyte, Oxford Immune Algorithmics, Sention Health and the Swedish Olympic Committee.
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Brodin, P. Platelet partnerships and lasting memories. Nat Immunol 26, 7–8 (2025). https://doi.org/10.1038/s41590-024-02040-3
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DOI: https://doi.org/10.1038/s41590-024-02040-3