Genes in transcription factor families presumably arose to accommodate the increasingly complex regulatory needs of multicellular organisms. A study now identifies the basis for distinction between the NF-κB family members Rel and RelA.
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The authors are supported by the Intramural Research Program of the National Institute on Aging.
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Sung, MH., Sen, R. Evolving Rel. Nat Immunol 26, 642–643 (2025). https://doi.org/10.1038/s41590-025-02142-6
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DOI: https://doi.org/10.1038/s41590-025-02142-6
