Antibiotic exposure in early life disrupts the infant microbiome, dampens vaccine responses and alters immune programming. Restoring Bifidobacterium may offer a microbiota-targeted strategy to enhance vaccine efficacy in vulnerable populations.
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Feng, Y., Pulendran, B. Antibiotics, microbiota and the calibration of infant vaccine responses. Nat Immunol 26, 810–811 (2025). https://doi.org/10.1038/s41590-025-02169-9
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DOI: https://doi.org/10.1038/s41590-025-02169-9
