Extended Data Fig. 7: Details of motif analysis regarding the positioning of blood CCR8⁺ T_reg cells.

a, Logos for motifs highlighted in Fig. 5d (obtained from homer). b, Chromatin accessibility around genomic sites for additional bZIP motifs. Parts of these plots are duplicated from Extended Data Fig. 4 as they correspond to the same motifs. c, Enrichment of bHLH motifs in methylation-level region sets defined by different blood CCR8⁺ T_reg cell positionings. P values, one-tailed binomial test implemented in homer assessing enrichment of motif sites among the region sets compared to background sets of random regions (see Methods; n = 6,424 DMRs and 292,033 DMRs for columns 1 and 2, respectively) with Benjamini-Hochberg correction. d, Motifs highlighted in c (obtained from homer). Parts of this figure are duplicated from Extended Data Fig. 5 as they correspond to the same motifs. Data are representative of two or more independent experiments with two or more individual donors.