Extended Data Fig. 10: Methylation and accessibility of HERVIP10F-int and LTR45B insertion sites.

a, Left, Methylation of annotated HERVIP10F-int and LTR45B insertion sites in skin T_reg, fat T_reg and blood CD45RA⁺ T_reg cells (n = 3 donors per cell type). White horizontal lines inside violins indicate medians across all insertion sites. Right, Distribution of differences in mean methylation (across the three donors) between any two cell types for each insertion site. Numbers indicate how many insertion sites displayed differences below and above 0. b, Chromatin accessibility of peaks overlapping with annotated HERVIP10F-int and LTR45B insertion sites in skin T_reg, blood CCR8⁺ T_reg and blood CD45RA⁺ T_reg cells. White horizontal lines inside violins indicate medians across all peaks. Data are representative of two or more independent experiments with two or more individual donors.