Extended Data Fig. 6: Additional data related to Fig. 6. | Nature Immunology

Extended Data Fig. 6: Additional data related to Fig. 6.

From: A STUB1–CHIC2 complex inhibits CD8+ T cells to restrain tumor immunity

Extended Data Fig. 6

(a) Pairwise structure alignment of crystal structures of the STUB1 TPR domain (human-8EHZ and 7TB1) and full-length STUB1 (mouse-2C2L). (b) Western Blots of IL-27Rα, phosphorylated p62 (positive control), β-ACTIN (loading control), and IFNγR1 following treatment of EL4 cells with vehicle or MG132 (performed twice). (c) Western Blots of V5, IL-27Rα, and IFNγR1 following V5 immunoprecipitation (left) and corresponding whole cell lysates with β-ACTIN loading control (right) of EL4 cells transduced with Chic2-V5-tagged cDNAs (performed twice).

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