Fig. 5: Immunohistochemistry of PECs and intracellular signaling molecules. | Nature Immunology

Fig. 5: Immunohistochemistry of PECs and intracellular signaling molecules.

From: Spatiotemporal interaction of immune and renal cells controls glomerular crescent formation in autoimmune kidney disease

Fig. 5: Immunohistochemistry of PECs and intracellular signaling molecules.The alternative text for this image may have been generated using AI.

a, Exemplified presentation of immunofluorescence staining showing prominent phospho-ERK1/2 and CD44 positivity in claudin-1+ or synaptopodin− PECs in human kidney biopsies of patients with ANCA-GN (bottom) compared to healthy control tissue (top). b, Exemplified presentation of immunofluorescence staining showing prominent phospho-SMAD3 staining in PAX8+ or synaptopodin− PECs in human kidney biopsies of patients with ANCA-GN (bottom) compared to healthy control tissue (top) in exemplified immunofluorescence staining. Representative staining of four controls and four patients with ANCA-GN is shown.

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