Extended Data Fig. 6: Hypoxia enhances TIM4-AMPKα signaling pathway.
From: Cancer suppresses mitochondrial chaperone activity in macrophages to drive immune evasion
(a-e) BMDMs were treated with TCM for 24 h under either normoxic or hypoxic conditions. Expression levels of TIM4 (a), p-AMPKα (b), TRAP1 (c), CD206 (d) and ARG1 (e) were assessed by flow cytometry (n = 4). Data are representative of two independent experiments. All data are mean ± s.e.m. and were analyzed using one-way ANOVA with Sidak’s multiple comparison test (a-e).
