Extended Data Fig. 7: SIRT2 deficiency does not impact Treg cell development.
From: SIRT2-mediated deacetylation of LCK governs the magnitude of T cell receptor signaling
a-c, representative flow-cytometric plots (left) and frequencies (right) of Treg cells based on CD44 and FoxP3 expressions in WT and Sirt2−/− thymi, lymph nodes and spleens from C57BL/6 (a), OT-II (b) and PMEL (c) mice. Each dot represents one mouse (n = 3 mice per group). Data are mean ± SEM. P values were determined by two-way ANOVA. Data are representative of two independent experiments.
