Extended Data Fig. 3: BACH2 overexpression alters CAR T cell lineage commitment in response to prolonged antigen stimulation.
From: BACH2 regulates T cell lineage state to enhance CAR T cell function
a, Representative flow cytometry of memory subtypes at day 6 of chronic stimulation. b, Memory subtype composition of bulk, CD4 and CD8 CAR T cells over the course of chronic stimulation. c, BACH2 expression in bulk, CD4 and CD8 CAR T cells at the end of chronic stimulation cultures. All data representative of n = 3 donors. All data are represented as either individual values or mean values ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 by two-way ANOVA with Bonferroni adjustment for multiple comparisons.
