Extended Data Fig. 3: RUNX1 is expressed in human mTECs.
From: Thymic alveolar type 2 epithelial mimetic cells revealed by RUNX1 deficiency
a-b, UMAPs (a) and violin plots (b) of marker genes from scRNA-seq data from sorted CD11c−/EpCAM+/Ly51− mTECs. c-d, scRNA-seq of human thymic epithelial cells. UMAP of human mTEC clusters and RUNX1 expression (c). Violin plot of RUNX1 expression (d). e, UMAP of scRNA-seq of MHC-IIlow mTECs from C57BL/6 mice merged with scRNA-seq from Foxn1-Cre(+)/Runx1+/+ mTECs to identify AT2 mTEC. Red numbers are the percentage of AT2 mTECs.
