Supplementary Figure 4: Sensitivity with and without corroborative DNase-seq data.
From: Comprehensive comparative analysis of 5′-end RNA-sequencing methods
Shown is the sensitivity (y-axis) for each method (x-axis). False negatives were defined as all TSSs without overlapping 5’ end RNA-Seq peaks (“without” DNase-Seq) or only the subset overlapping DNase-Seq peaks in K-562 cells (“with” DNase-Seq, the method used in Fig. 4). DNase-Seq data permits better assessment of actual performance for K-562 cells rather than comparing only to the UCSC annotation, which is compiled from diverse samples.
