Supplementary Figure 8: TSS initiator sequences.
From: Comprehensive comparative analysis of 5′-end RNA-sequencing methods
For each method, shown are the nucleotides right before (−1 position) and after (+1 position) the dominant TSS for each tag cluster (TC). The results are displayed as sequence logos for (a) broad TCs and (b) narrow TCs. Although the methods differ in the nucleotide distributions, in all cases, we do see a preference for a pyrimidine at position −1 and a purine at position +1, as has been found previously.
