Supplementary Figure 1: Fragmentation of asymmetric and symmetric sulfoxide moieties. | Nature Methods

Supplementary Figure 1: Fragmentation of asymmetric and symmetric sulfoxide moieties.

From: EASI-tag enables accurate multiplexed and interference-free MS2-based proteome quantification

Supplementary Figure 1

Fragments generated upon HCD-induced cleavage of an asymmetric sulfoxide site as it is present in EASI-tag (left panel) and of a symmetric sulfoxide site as it is present in MS-cleavable crosslinkers (right panel). Here, ‘asymmetry’ refers to the different chemical constitution of the residues on either side of the sulfoxide.

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