Supplementary Figure 3: High consistency between Trac-looping and ATAC-seq in detection of chromatin accessibility. | Nature Methods

Supplementary Figure 3: High consistency between Trac-looping and ATAC-seq in detection of chromatin accessibility.

From: Trac-looping measures genome structure and chromatin accessibility

Supplementary Figure 3: High consistency between Trac-looping and ATAC-seq in detection of chromatin accessibility.

(a) Distribution of PET-end density around transcription start sites (TSSs) for PETs sorted by distance. (b) Scatter plot showing tag density for ATAC-seq in fixed cells (x-axis) and unfixed cells (y-axis) at all accessible sites (n=64,316). (c) Scatter plot showing tag density for ATAC-seq and Trac-looping in fixed cells at all accessible sites (n=64,316). (d) Scatter plot showing tag density of ATAC-seq and Trac-looping in fixed cells at promoters (left; n=8,098), enhancers (middle; n=18,425) and CTCF sites (right; n=12,906). (b-d): The R value is the Pearson’ correlation coefficient.

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