Supplementary Fig. 1: Functional coherence of scRNA-seq gene coexpression networks, considering all datasets from each publication (n = 213).

Functional coherence of single-cell gene coexpression networks. Known gene functions were randomly withheld and predicted from the coexpression network in threefold cross-validation, and the area under the receiver operating characteristic curve (AUC) was calculated to quantify the degree to which genes with similar functions are coexpressed in networks constructed with each measure of association. Box plots show median (horizontal line), interquartile range (hinges) and the smallest and largest values no more than 1.5 times the interquartile range (whiskers).