Supplementary Figure 7: Summary of T7 endonuclease I (T7E1) assay results for DNA mismatch cleavage in OVCAR8-ADR cells.
From: Combinatorial mutagenesis en masse optimizes the genome editing activities of SpCas9
Cells were infected with an SpCas9 variant and the indicated gRNA, and genomic DNA were collected for T7E1 assay after 11 to 16 days post-infection. Indel quantification for the infected samples is displayed as a bar graph.
