Supplementary Figure 9: Performance of BindSpace, PWM, LASSO and DeepBind for distinguishing NR2F6 specific peaks versus NR2F1 specific peaks in HepG2.
From: BindSpace decodes transcription factor binding signals by large-scale sequence embedding
From top to bottom, we show the results for BindSpace, PWM, LASSO and DeepBind. From left to right for each method, we show the predicted scores of NR2F6 specific peaks (n=3819), NR2F1 specific peaks (n=3819), and common peaks (n=6188) in the scatter plots. One-sided Wilcoxon signed-rank test P values are reported in the top right corner. Each probe is assigned to be NR2F6 specific (red), NR2F1 specific (blue) or low affinity (gray). See Methods for empirical thresholds for predicting low affinity (negative) probes for each method. Pie charts show the proportion of NR2F6 specific peaks versus NR2F1 specific peaks in each group.
