Supplementary Figure 10: Statistical features of identified m1A sites from m1A-IP-seq.
From: Evolution of a reverse transcriptase to map N1-methyladenosine in human messenger RNA
a, Enriched motif found surrounding n = 281 m1A sites identified in m1A-IP-seq, with P < 0.05 based on the beta-binomial regression test in mRNA and lncRNA. The enrichment score of the shown motif has an E-value of 9.2 × 10–5, calculated by the MEME Suite program (Methods), contributed from 68 out of 281 input sequences. b, Distribution of transcript localizations of 215 m1A sites in mRNA is shown by the pie chart and Metagene plot processed by the ‘Guitar’ R package (Methods).
