Extended Data Fig. 5: Average responses to unilateral hind-paw stimulation.
From: Simultaneous cortex-wide fluorescence Ca2+ imaging and whole-brain fMRI
a, Average responses to nine stimuli across N = 6 mice. Stimulus onset is denoted by black triangles. Ca2+ data (top) and the corresponding fMRI data (bottom) are plotted. The fMRI signal is normalized to the mean. The standard deviation within the responding ROI is shown as shading. b, The average normalized (to peak amplitude), stimulus response across N = 6 mice, n = 9 stimuli each. This shows the different temporal dynamics of these two modalities. The fMRI signal is delayed, relative to stimulus presentation and the Ca2+ signal. c) A zoomed in view of the Ca2+ and BOLD signals. Since the Ca2+ signal is collected at a relatively high temporal resolution (10 Hz), it appears in to be noisy. By zooming in the fast kinetics of these data are shown. No filtering of the Ca2+ signal has been applied.
