Extended Data Fig. 6: Localization of Ca2+ and fMRI responses to stimuli.
From: Simultaneous cortex-wide fluorescence Ca2+ imaging and whole-brain fMRI
a, A surface projection of the down-sampled Allen Atlas overlaid on the optical data of an example mouse. The ROI expected to respond to the presented unilateral hind limb stimuli is indicated with a dotted line. b, Responding ROIs from all mice from both modalities normalized to the maximum response amplitude. Calculated as follows if we had two instead of six mice: if voxel (i,j) for mouse #1 on average showed a 40% response relative to the maximum responding voxel for that mouse, and voxel (i,j) for mouse #2 on average showed a 60% response relative to the maximum responding voxel for mouse #2, then voxel (i,j) would be color-coded to 50%. The expected responding ROI from the Allen Atlas is shown as a dotted line. c, An example responding ROI from one mouse overlaid on the optical data. d, The same example responding ROIs (from the same mouse) overlaid on the projected MRI data.
