Extended Data Fig. 7: Experimental M2-seq z-score plots.
From: Accelerated cryo-EM-guided determination of three-dimensional RNA-only structures
(a) Tetrahymena ribozyme (n = 65041 sequences), (b) hc16 product (n = 459852 sequences), (c) hc16 (n = 451568 sequences), (d) human scaRNA6 (n = 866158 seqeunces), (e) V. cholerae glycine riboswitch with glycine (n = 928767 sequences), (f) V. cholerae glycine riboswitch without glycine (n = 974343 sequences), (g) human RB1 5′ UTR (n = 889700 sequences), (h) 24-3 (n = 515486 sequences), (i) human U1 snRNA (n = 1185187), (j) F. nucleatum glycine riboswitch with glycine (n = 803254 sequences), (k) F. nucleatum glycine riboswitch without glycine (n = 670301 sequences), (l) eterna3D-JR_1 (n = 994048 sequences), (m) spinach-TTR-3 (n = 1090666 sequences), (n) ATP-TTR-3 with AMP (n = 914892 sequences), (o) ATP-TTR-3 without AMP (n = 712801 sequences), (p) SAM IV riboswitch with SAM (n = 131464 sequences), (q) SAM IV riboswitch without SAM (n = 991972 sequences), and (r) downstream peptide riboswitch (n = 1012081 sequences).
