Extended Data Fig. 10: Benchmarking auto-DRRAFTER accuracy.
From: Accelerated cryo-EM-guided determination of three-dimensional RNA-only structures
(a–h) The top ten scoring auto-DRRAFTER models (models #2-10 are transparent) built into 10 Å simulated density maps (left) and the corresponding crystal structures (right) for (a) THF riboswitch, (b) c-di-AMP riboswitch, (c) bacterial SRP Alu domain, (d) FMN riboswitch, (e) SAM-I riboswitch, (f) Tetrahymena ribozyme P4-P6 domain, (g) lysine riboswitch, and (h) lariat capping ribozyme. (i) Ribosolve models for THF riboswitch built into the previously solved 2.9 Å crystallographic density map (left) and the crystal structure (right). (j) Ribosolve models for the B. subtilis T-box-tRNA complex built into a 4.9 Å cryo-EM map (left) and previously modeled coordinates (right) based on high-resolution crystal structures30. Helical regions are depicted with bright colors. Non-helical regions are colored gray.
