Extended Data Fig. 3: Transmission electron micrographs of ARG-expressing E. coli Nissle cells after imaging.
From: Ultrasensitive ultrasound imaging of gene expression with signal unmixing
(a) Representative cell from a sample not imaged with BURST or BURST+. A total of 14 micrographs of cells in this condition were acquired with similar results. (b) Representative cell from a sample imaged with BURST. A total of 13 micrographs of cells in this condition were acquired with similar results. (c) Representative cell from a sample imaged with BURST+. A total of 16 micrographs of cells in this condition were acquired with similar results. All scalebars: 500 nm. GVs are visible inside the control cell as lighter objects, and are absent in the imaged cells.
