Fig. 4: The 4DN-BINA Light Microscopy Metadata Specifications extend the core of the OME Data Model.

Portrayed are Venn diagrams containing a linked-open-data (LOD; Fig. 6b) representation of the core vs. extension relation between metadata model elements that belong to the core of the OME Data Model (OME) namespace (blue ovals) and those that belong to the three proposed extensions specified by the 4DN-BINA-OME (NBO) namespace (maroon, gray and green ovals). Specifically, the schema illustrates the relationship between the <Instrument> (a) and <Image> (b) elements (OME: Instrument, OME: Image; red-bordered blue ovals) and their subelements belonging to the core of the OME Data Model (light blue set containing blue ovals; for example, OME: Filter, OME: Channel, etc.), with subelements specified by the 4DN-BINA-OME extensions Calibration and Performance (light red set containing maroon ovals; for example, NBOC: LightSensor, NBOC: OpticalCalibration, etc.), Basic (light gray set containing dark gray ovals; for example, NBOB: OpticalAperture, NBOB: CameraSettings, etc.), and Advanced and Confocal (light green set containing green ovals; for example, NBOA: SpinningDisk, NBOA: PinHoleSettings, etc.). The schema is not intended to be comprehensive and includes only a small subset of the elements that comprise the model. AOBS, acousto-optical beam splitter; AOTF, acousto-optical tunable filter; LCTF, liquid crystal tunable filter; TIRF, total internal reflection.