Extended Data Fig. 9: Analysis of combined intestinal organoid and crypt data. | Nature Methods

Extended Data Fig. 9: Analysis of combined intestinal organoid and crypt data.

From: Deterministic scRNA-seq captures variation in intestinal crypt and organoid composition

Extended Data Fig. 9

(a) Combined UMAP embedding (as shown in Fig. 5d) stratified by the five individual batches of intestinal crypt samples and the three independent experimental batches of intestinal organoid differentiation samples, collectively embedded and colored by cluster annotation. (b) UMAP-based visualization of the expression of specific markers that were used for cluster annotation. (c) Bar graph depicting the cumulative Z-score of the expression of genes that are indicated within the respective bar graph. CanStem: canonical stem cell, RegStem: regenerative stem cell.

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