Fig. 3: Exploring the protein localization atlas.
From: Self-supervised deep learning encodes high-resolution features of protein subcellular localization
a, Representative images of proteins localized along an exemplary path across the nuclear-cytoplasmic transition and over the ‘gray’ space of mixed localizations. b, The subunits of well-known and stable protein complexes tightly cluster together. Moreover, the complexes themselves are placed in their correct cellular contexts. Different proteins have different expression levels, hence we adjusted the brightness of each panel so as to make all localizations present in each image more visible (only minimum–maximum intensities are adjusted, no gamma adjustment used). All representative images were randomly selected. Protein localization is displayed in grayscale in both panels, the nuclei in b are displayed in blue. The list of the subunits of each complex are indicated in Supplementary File 5. Scale bars, 10 μm.
