Extended Data Fig. 6: Effect of shield-1 on transcription-activation domain expression. | Nature Methods

Extended Data Fig. 6: Effect of shield-1 on transcription-activation domain expression.

From: A general method for chemogenetic control of peptide function

Extended Data Fig. 6

Related to main Fig. 5. a, Quantification of reporter gene activation level (mCherry, left) and transcription-activation domain expression marker level (EGFP, right). n = 12 fields of view from one replicate for all conditions. b, No difference in reporter expression was found between the + shield-1 and – shield-1 conditions in the control study with SspB-EGFP-VP16 only. n = 12 fields of view from one replicate for all conditions. All scale bars, 50 µm. P values are determined by unpaired two-tailed t-tests. **P < 0.01; ***P < 0.001; ****P < 0.0001; NS, not significant. This experiment was performed three times with similar results.

Source data

Back to article page