Extended Data Fig. 8: FD-DeepLoc enables large FOV whole cell 3D super-resolution imaging of NPC.
From: Field-dependent deep learning enables high-throughput whole-cell 3D super-resolution imaging
a, Overview of the panoramic whole cell 3D super-resolution image of NPC. b, Different axial sections of a. b1-3 are top views of axial range of (0 μm–2 μm), (2 μm–3 μm) and (3 μm – 5 μm), respectively. c, Magnified views of areas denoted by box c in a. c1, Top view of the box c area denoted in a. c2, Side-view cross-section of region denoted by the dashed line in c1. c3-4 are zoomed views of the top and bottom surface of the boxed area denoted in c1. d, Same as c for magnified views of region denoted by box d in a. e, The distribution of the fitted radii of the NPCs for the cell in c. e1 and e2 are for the top and bottom nucleus surface, respectively. f is the same as e, but for the cell in d. Representative results are shown from 7 experiments. Scale bars, 50 μm (a, b1), 5 μm (c1, c2, d1, d2) and 1 μm (c3, d3).
