Extended Data Fig. 3: Longitudinal variation at the pathways and gene-level. | Nature Methods

Extended Data Fig. 3: Longitudinal variation at the pathways and gene-level.

From: Microbial-enrichment method enables high-throughput metagenomic characterization from host-rich samples

Extended Data Fig. 3: Longitudinal variation at the pathways and gene-level.The alt text for this image may have been generated using AI.

PCA analysis was performed on all 60 longitudinal samples grouped by participant (CT7, CT8, CT12, CT13, and CT14). Shotgun-sequencing data was annotated for pathways and genes through HUMAnN 3 without the taxonomic-profile flag. A) PCA on relative abundance of all pathways. B) PCA on relative abundance of completed pathways (defined as above 90% of modules being present). C) PCA on relative abundance of all genes. D) PCA on relative abundance of the top 5,000 most abundant genes in each participant.

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