Extended Data Fig. 4: Effects of CytoD on the mechanics of MEFs.
a, Representative timelapse confocal imaging of paxillin-GFP, 17pN-RSDTPs, TFM of cells spreading on 30 kPa PA hydrogel before and after treatment of cytochalasin D (20 μM), and corresponding plots of b, total intensity of mTFM and c, total traction forces measured by TFM (Control, n = 44 cells. CytoD, n = 41 cells). Data represent mean ± s.d. of three experiments. Two-tailed Student t-test is used to assess statistical significance.
