Extended Data Fig. 3: Robustness assessment of CytoCommunity performance using different granularity of annotated cell types.
From: Unsupervised and supervised discovery of tissue cellular neighborhoods from cell phenotypes
Mouse hypothalamic preoptic region MERFISH dataset was used due to the complex cell types in this tissue. (a) Cell types and TCNs identified using 9 coarse-grained cell type annotations as the input. (b) Cell types and TCNs identified using 15 fine-grained cell type annotations as the input. Both sets of cell type annotations were downloaded from the original study17. (c) Robustness score is defined as the average Jaccard index between the two sets of TCNs generated using the two sets of cell type annotations.
