Extended Data Fig. 4: Enrichment score plots from I-Ag7 Library Validations.
A. The enrichment score plots for each of 8-independent replicate screen of the BDC2.5 TCR against the I-Ag7-SABR-II library. The resulting high and low confidence thresholds are denoted by green and orange lines respectively. B. The enrichment score for each of 3-independet replicate screen of the 4–8Ins TCR against the SABR-II library. The same high and low confidence thresholds as maintained from experiments in panel A. For every plot each dot represents a single epitope spread across the x-axis and red dots indicate putative cognate epitopes selected for validation.
