Extended Data Fig. 5: Reduced dataset diversity disproportionately affects global structure. | Nature Methods

Extended Data Fig. 5: Reduced dataset diversity disproportionately affects global structure.

From: OpenFold: retraining AlphaFold2 yields new insights into its learning mechanisms and capacity for generalization

Extended Data Fig. 5: Reduced dataset diversity disproportionately affects global structure.

Mean GDT-TS and lDDT-Cα of non-overlapping protein fragments from CAMEO validation set as a function of the percentage of CATH clusters in elided training sets. Data for both topology and architecture elisions are included. The fragmenting procedure is the same as that described in Fig. 5a.

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