Scientific breakthroughs can change how we understand and live in the world, disrupting long-held assumptions and concepts and raising new questions for philosophy and science. To address these challenges, we describe a model for collaboration of scientists with philosophers and ethicists, and its benefits to the research process and outcomes.
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References
Knoppers, B. M. & Chadwick, R. Nat. Rev. Genet. 6, 75–79 (2005).
Institute of Medicine and National Research Council. Final Report of the National Academies’ Human Embryonic Stem Cell Research Advisory Committee and 2010 Amendments to the National Academies’ Guidelines for Human Embryonic Stem Cell Research (National Academies Press, 2010); https://doi.org/10.17226/12923
de Graeff, N., De Proost, L. & Munsie, M. Nat. Methods 20, 1863–1867 (2023).
Aach, J., Lunshof, J., Iyer, E. & Church, G. M. eLife 6, e20674 (2017).
Lopes, M. et al. Am. Sci. 109, 208–209 (2021).
Kriegman, S., Blackiston, D., Levin, M. & Bongard, J. Proc. Natl. Acad. Sci. USA 117, 1853–1859 (2020).
Panizzolo, F. A. et al. J. Neuroeng. Rehabil. 13, 43–56 (2016).
Urbina, F., Lentzos, F., Invernizzi, C. & Ekins, S. Nat. Mach. Intell. 4, 189–191 (2022).
Tolikas, M., Antoniou, A. & Ingber, D. E. Bioeng. Transl. Med. 2, 247–257 (2017).
Guerrini, C. J., Curnutte, M. A., Sherkow, J. S. & Scott, C. T. Nat. Biotechnol. 35, 22–24 (2017).
Lovell-Badge, R. et al. Stem Cell Reports 16, 1398–1408 (2021).
Lancaster, M. A. et al. Nature 501, 373–379 (2013).
Pașca, S. P. et al. Nature 609, 907–910 (2022).
Hyun, I. et al. Nat. Neurosci. 25, 1399–1401 (2022).
Levin, M., Bongard, J. & Lunshof, J. E. Nat. Rev. Mol. Cell Biol. 21, 655–656 (2020).
Gumuskaya, G. et al. Adv. Sci. 11, 2303575 (2024).
Boogerd, F. C., Bruggeman, F. J., Hofmeyr, J. H. S. & Westerhoff, H. V. In Systems Biology edn. 1 (eds Boogerd, F. C., Bruggeman, F. J., Hofmeyr, J. H. S. & Westerhoff, H. V.) 3–19 (Elsevier, 2007).
Grosz, B. J. et al. Commun. ACM 62, 54–61 (2019).
Begley, S. STAT News. https://www.statnews.com/2018/11/27/crispr-babies-creator-soaked-up-bioethics/ (2018).
Acknowledgements
The authors wish to thank Benjamin Boettner and Seth Kroll of the Wyss Institute for discussion and media support. J.R. gratefully acknowledges funding through the Dutch Research Council (NWO) program Ethics of Socially Disruptive Technologies, grant no. 024.004.031
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J.E.L. developed the model. J.E.L. and J.R. wrote the manuscript.
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Lunshof, J.E., Rijssenbeek, J. Collaborative ethics: innovating collaboration between ethicists and life scientists. Nat Methods 21, 1571–1574 (2024). https://doi.org/10.1038/s41592-024-02320-8
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DOI: https://doi.org/10.1038/s41592-024-02320-8
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