Fig. 4: DynaMight results for the CCAN–CENP-A complex.
From: DynaMight: estimating molecular motions with improved reconstruction from cryo-EM images
a, Principal components analysis (PCA) of the conformational latent space, with colored dots indicating the positions of the five maps in b. (Only the latent space for one of the two half sets is shown.) b, Five conformational states of the complex. One state, in red, is shown in all four panels. The colors of the five maps are the same as the colors of their corresponding dots in a. c, Reconstructions from standard RELION consensus refinement. d, The improved reconstruction using DynaMight. The maps in c and d are colored according to local resolution, as indicated by the color bar.
