Extended Data Fig. 10: Stochastic fluctuation of vision: V1 activity and running dynamics during high-ramp and low-ramp trials.
From: Moculus: an immersive virtual reality system for mice incorporating stereo vision
(see Supplementary Note 1 for details). a, Left, average neuronal activity and running speed during high ramps in the aversive zone (mean ± SEM), similar to Fig. 6j but normalized to show relative time delay. Middle, average activity (n = 85 cells: red) and running (blue) during three representative high-ramp trials. Right, activity and running speed for one example cell. Red arrows indicate that neuronal activity precedes running during high ramps. b, Same as panel a but for low-ramp trials (mean ± SEM). Blue arrows indicate that running precedes neuronal activity. c, Top: Correlation between running start time and the average ramp onset times for individual trials, dashed line (x = y) and red arrow indicate trials where V1 activity preceded running (Pearson’s r = 0.93). Middle top: Delay between neuronal activity and running vs. ramp amplitude (Pearson’s r = 0.87). Red and blue triangles indicate trials where V1 activity preceded or followed motor activity, respectively. Middle bottom: Delay between neuronal activity and running vs. ramp timing (Pearson’s r = -0.94). Bottom: running onset vs. ramp amplitude. d, Similar to Fig. 6j, but for a single neuron. Calcium activity and velocity curves were presented as mean values ± SEM. e, Similar to Fig. 6f and 6i, but for neuron in panel d. f, Same as Fig. 6g and the third row of panel c but for neuron in panel d. Due to character limitations, the exact Pearson’s r values are provided in the figure.
