Extended Data Fig. 1: Interpretation and validation of the edited PPIF enhancer.
From: gReLU: a comprehensive framework for DNA sequence modeling and design
a) ISM sequence logos of a subsequence in the edited PPIF enhancer, showing the emergence of new motifs. b) Predicted change in the probability of chromatin accessibility across the PPIF enhancer in T-cell/Jurkat-like and Monocyte/THP-1 like tracks using an orthogonal binary classification model trained to predict ATAC-seq peaks from DNA sequence.
