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Method of the Year: EM connectomics

Using electron microscopy, scientists mapped a Caenorhabditis elegans nervous system and Drosophila brain at single-neuron resolution. Connectomics work on bigger brains takes new methods strategies.

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Correspondence to Vivien Marx.

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Marx, V. Method of the Year: EM connectomics. Nat Methods 22, 2470–2475 (2025). https://doi.org/10.1038/s41592-025-02906-w

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