Extended Data Fig. 10: Comparison of ETciD, ECD and ETD spectra of four triply charged peptides from different datasets. | Nature Methods

Extended Data Fig. 10: Comparison of ETciD, ECD and ETD spectra of four triply charged peptides from different datasets.

From: Integration of alternative fragmentation techniques into standard LC-MS workflows using a single deep learning model enhances proteome coverage

Extended Data Fig. 10: Comparison of ETciD, ECD and ETD spectra of four triply charged peptides from different datasets.The alternative text for this image may have been generated using AI.

Comparison among spectra of triply charged AKVDATAETDLAKRF (a), KDPLLASGTDGVGTKL (b), KVPAINVNDSVTKSKF (c) and RAAGEQEKLEATNRY (d) peptide. Each panel contains ETciD spectrum acquired on Ascend Tribrid (this work), ETciD spectrum modeled by Prosit_Multifrag model, ETD spectrum acquired on Ascend Tribrid (Sinitcyn et al., Ref. 39), ECD spectrum acquired on Exploris-Omnitrap (this work). PCC number is the Pearson correlation coefficient between the spectrum and the ETciD prediction.

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