Extended Data Fig. 3: Electrical characterization and light artifact removal.
From: Neuropixels Opto: combining high-resolution electrophysiology and optogenetics
a. Input-referred RMS noise levels, measured in saline for 957 recording sites from N = 21 probes, in the AP band. Each dot represents a measurement for one site for one probe. Yellow line indicates the median across all probes. b. Same, for the LFP band. c. Measurements in brain tissue during light activation, showing light artifact for 10 ms red light pulses at 100 μW in the AP band (average of 30 trials, 384 recording sites). The red and blue bars indicate periods of light activation (20 Hz train of 10 ms light pulses). d. Same, for the LFP band. e. Because the artifact seen for red pulses is highly uniform across recording sites, it is removed by phase shifting and median subtraction of the AP band data. f. In the LFP band, the small transients at the onset and offset of each pulse of red light are removed by applying a bandpass filter between 0.1 and 300 Hz.
